Search Results: adverse-effects-of-engineered-nanomaterials

Adverse Effects of Engineered Nanomaterials

Exposure, Toxicology, and Impact on Human Health

Author: Bengt Fadeel,Antonio Pietroiusti,Anna A. Shvedova

Publisher: Academic Press

ISBN: 0128094907

Category: Medical

Page: 486

View: 6070

Adverse Effects of Engineered Nanomaterials: Exposure, Toxicology, and Impact on Human Health, Second Edition, provides a systematic evaluation of representative engineered nanomaterials (ENM) of high volume production and their high economic importance. Each class of nanomaterials discussed includes information on what scientists, industry, regulatory agencies, and the general public need to know about nanosafety. Written by leading international experts in nanotoxicology and nanomedicine, this book gives a comprehensive view of the health impact of ENM, focusing on their potential adverse effects in exposed workers, consumers, and patients. All chapters have been updated with new sections on the endocrine system and other organ systems. In addition, other newly added sections include introductory chapters on the physio-chemical characterization of nanomaterials and interactions between nanomaterials and biological systems, as well as a new chapter that explores risk assessment and management of nanomaterials. This book fills an important need in terms of bridging the gap between experimental findings and human exposure to ENM, also detailing the clinical and pathological consequences of such exposure in the human population. Uses a schematic, non-exhaustive approach to summarizes the most important research data in this field Discusses the health implications of experimental data in nanotoxicology Presents a completely revised edition that focuses on the human health impacts of engineered nanomaterials, including many organ-specific chapters

Biological Monitoring

Heutige und Kunftige Moglichkeiten in der Arbeits- und Umweltmedizin

Author: Jurgen Angerer

Publisher: John Wiley & Sons

ISBN: 3527621210

Category: Science

Page: 218

View: 4848

Auf Einladung der Deutschen Forschungsgemeinschaft (DFG) fand am 9. und 10. März 2000 ein Rundgespräch über heutige und künftige Möglichkeiten des Biomonitoring in Arbeits- und Umweltmedizin statt. Das Biomonitoring hat nicht zuletzt durch die unmittelbare Umsetzung der Arbeitsergebnisse der Senatskommission zur Prüfung gesundheitsschädlicher Arbeitsstoffe in geltendes Recht durch die deutsche Arbeitsschutzgesetzgebung in den letzten dreißig Jahren in Deutschland ein hohes Niveau erreicht. Das vorliegende Buch führt die Expertise verschiedener Fachdisziplinen von der Toxikologie, Arbeitsmedizin, Immunologie und Humangenetik bis hin zur Analytik und Epidemiologie zusammen. Hierbei wird die diagnostische Aussagekraft von zytogenetischen Parametern sowie von biochemischen und biologischen Effektmarkern für die Prävention von schadstoffbedingter Erkrankungen ausführlich erörtert. Das geführte Rundgespräch hat somit einen ersten Gedankenaustausch ermöglicht, aus dem sich künftige Forschung entwickeln soll, um die führende Rolle Deutschlands auf diesem wichtigen und sich dynamisch entwickelnden Forschungsgebiet zu halten.

Engineered Nanoparticles

Structure, Properties and Mechanisms of Toxicity

Author: Ashok K Singh

Publisher: Academic Press

ISBN: 012801492X

Category: Medical

Page: 554

View: 1883

Engineered Nanoparticles: Structure, Properties and Mechanisms of Toxicity is an indispensable introduction to engineered nanomaterials (ENM) and their potential adverse effects on human health and the environment. Although research in the area of pharmacology and toxicology of ENM is rapidly advancing, a possible correlation between their physicochemical properties and biomedical properties or toxicity is not yet fully understood. This understanding is essential to develop strategies for the safe applications and handling of ENM. The book comprehensively defines the current understanding of ENM toxicity, first describing these materials and their physicochemical properties, and then discussing the toxicological theory and methodology before finally demonstrating the potential impact of ENM on the environment and human health. It represents an essential reference for students and investigators in toxicology, pharmacology, chemistry, material sciences, medicine, and those in related disciplines who require an introduction to ENM and their potential toxicological effects. Provides state-of-the-art physicochemical descriptions and methodologies for the characterization of engineered nanomaterials (ENM) Describes the potential toxicological effects of ENM and the nanotoxicological mechanisms of action Presents how to apply theory to practice in a public health and risk assessment setting

Handbook of Immunological Properties of Engineered Nanomaterials

Author: Marina A. Dobrovolskaia,Scott E. McNeil

Publisher: World Scientific

ISBN: 9814390259

Category: Medical

Page: 692

View: 5568

The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Nanotoxicity

From In Vivo and In Vitro Models to Health Risks

Author: Saura C. Sahu,Daniel A. Casciano

Publisher: John Wiley & Sons

ISBN: 047074779X

Category: Science

Page: 630

View: 4090

Nanomaterials - substances smaller than 100 nanometers in size - have been added in recent years to an increasing numbers of consumer products used in day-to-day life; in food packaging, medical devices, pharmaceuticals, cosmetics, odor-resistant textiles and household appliances. The extensive application of nanomaterials in a wide range of products for human use poses a potential for toxicity risk to human health and the environment. Such adverse effects of nanomaterials on human health have triggered the development of a new scientific discipline known as “nanotoxicity” – the study of the toxicity of nanomaterials. Nanotoxicity: From in vivo and in vitro Models to Health Risks provides up-to-date state-of-the-art information presented by recognized experts in this emerging new field in toxicology. It discusses the safety evaluation of nanomaterials in foods, drugs, medical devices, cosmetics and other regulated products and its use in risk analysis for potential regulatory use. Topics covered include: biomarkers for nanotoxicity assessment nanotoxicity assessment by gene expression analysis in vivo and in vitro models for nanotoxicity testing mechanisms of nanotoxicity pharmakokinetics of nanomaterials nanotoxicity of foods including food processing, food packaging and food safety nanotoxicity of drugs including drug development and drug delivery nanotoxicity of cosmetics and consumer products health and environmental impact of nanotoxicity safety evaluation of nanomaterials regulatory impact of nanomaterials Nanotoxicity: From in vivo and in vitro Models to Health Risks is a valuable authoritative source of information for readers from a wide range of disciplines such as toxicology, pharmacology, drug toxicity and food and environmental sciences. The book will be useful to the research community in academia, industry, hospitals and government, as well as to government regulators and risk assessors of foods, drugs and environmental and agricultural products.

Nanotechnology - Toxicological Issues and Environmental Safety

Author: P.P. Simeonova,N. Opopol,M.I. Luster

Publisher: Springer Science & Business Media

ISBN: 1402060769

Category: Technology & Engineering

Page: 276

View: 3241

This book provides a summary of the state-of-art knowledge on nanomaterials and nanoparticles. It examines toxicological issues, risk assessment and control measures, public participation and educational/ethical issues, as well as institutional mechanisms and status reports from various countries. Coverage also details collaborations in the field of nanotechnology regarding safe application and development.

Phytotoxicity of Nanoparticles

Author: Mohammad Faisal, Quaiser Saquib, Abdulrahman A. Alatar and Abdulaziz A. Al-Khedhairy

Publisher: Springer

ISBN: 3319767089

Category:

Page: N.A

View: 564

Case Studies in Nanotoxicology and Particle Toxicology

Author: Antonietta M Gatti,Stefano Montanari

Publisher: Academic Press

ISBN: 0128012544

Category: Medical

Page: 276

View: 2191

Case Studies in Nanotoxicology and Particle Toxicology presents a highly-illustrated analysis of the most prominent cases on the adverse effects of nanoparticles and their impact on humans and the environment. This comprehensive reference demonstrates the possible risks imposed by managing and handling nanoparticles, showing the effects of involuntary inhalation or ingestion during their use and after their incineration. Through the use of numerous examples, readers will discover the possible risks and effects of working with nanoparticles, along with best practices to prevent these effects. The text is an essential reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians. Presents real-life cases showing the potential risks to human health following exposure to nanoparticles An ideal reference for anyone working in the risk assessment of nanoparticles, including nanosafety professionals, occupational toxicologists, regulatory toxicologists, and clinicians Provides examples to help assess risks of handling engineered nanomaterials Advises on the best forms of protection and the safest nanotechnological products

The Environmental Applications and Implications of Nanotechnology in Membrane-based Separations for Water Treatment

Author: Wenqian Shan

Publisher: N.A

ISBN: N.A

Category: Electronic dissertations

Page: 256

View: 8023

Nanotechnology and Environmental Health and Safety: Issues for Consideration

Author: N.A

Publisher: DIANE Publishing

ISBN: 1437982484

Category: Nanotechnology

Page: 45

View: 4291

Handbook of Nanosafety

Measurement, Exposure and Toxicology

Author: Ulla Vogel,Kai Savolainen,Qinglan Wu,Martie van Tongeren,Derk Brouwer,Markus Berges

Publisher: Elsevier

ISBN: 0124166628

Category: Medical

Page: 376

View: 9857

Handbook of Nanosafety: Measurement, Exposure and Toxicology, written by leading international experts in nanosafety, provides a comprehensive understanding of engineered nanomaterials (ENM), current international nanosafety regulation, and how ENM can be safely handled in the workplace. Increasingly, the importance of safety needs to be considered when promoting the use of novel technologies like ENM. With its use of case studies and exposure scenarios, Handbook of Nanosafety demonstrates techniques to assess exposure and risks and how these assessments can be applied to improve workers' safety. Topics covered include the effects of ENM on human health, characterization of ENM, aerosol dynamics and measurement, exposure and risk assessment, and safe handling of ENM. Based on outcomes from the NANODEVICE initiative, this is an essential resource for those who need to apply current nanotoxicological thinking in the workplace and anyone who advises on nanosafety, such as professionals in toxicology, occupational safety and risk assessment. Multi-authored book, written by leading researchers in the field of nanotoxicology and nanosafety Features state-of-the-art physical and chemical characterization of engineered nanomaterials (ENM) Develops strategies for exposure assessment, risk assessment and risk management Includes practical case studies and exposure scenarios to demonstrate how you can safely use ENM in the workplace

Nanotoxicology

Characterization, Dosing and Health Effects

Author: Nancy A. Monteiro-Riviere,C. Lang Tran

Publisher: CRC Press

ISBN: 9781420045154

Category: Medical

Page: 392

View: 9280

Nanomaterials - structures with characteristic dimensions between 1 and 100 nm -exhibit a variety of unique and tunable chemical and physical properties that have made engineered nanoparticles central components in an array of emerging technologies. The use of nanotechnology is increasing; however its potential adverse effects on human health are not well understood. In order to accurately conduct hazard assessments, scientists need to understand the broad concepts that apply to pathways of dermal, oral, and respiratory exposure. This title is designed to elucidate those concepts and to examine the interaction of nanomaterials with the biological system, including membrane transfer, screening methods, and impact on major organs.

Environmental Nanotechnology, Applications and Impacts of Nanomaterials, Second Edition

Author: Mark Wiesner,Jean-Yves Bottero

Publisher: McGraw Hill Professional

ISBN: 0071828451

Category: Technology & Engineering

Page: 320

View: 4822

Extensively revised and featuring new material, this timely, advanced resource covers the impacts of nanomaterials on organisms and ecosystems and their applications within industry. Cowritten by leaders of two of the most prominent research groups in the world considering the effects of nanomaterials on the environment, the second edition of Environmental Nanotechnology addresses the cutting-edge advances in this area. There is now much more known about the impacts of nanomaterials on organisms and ecosystems. Methods have been developed where there were few accepted procedures in the past. Thinking has evolved to consider the life cycle effects of nanomaterial production, and tools for risk forecasting are now under development. There has also been some experience among academics in using this book as the basis for new courses on Environmental Nanotechnology. Three new chapters cover the life cycle of nanomaterial fabrication and use and estimating nanomaterial exposure in the environment. A systematic discussion of the effects of nanomaterials on organisms and ecosystems is included, where the previous edition was largely limited to speculation. Features 75% new material New chapter on the life cycle aspects of nanomaterial fabrication and use Two new chapters on estimating nanomaterial exposure in the environment: implications that explore nanotoxicology; exposure estimation Contains end-of-chapter problems and questions

The Handbook of Nanomedicine

Author: Kewal K. Jain

Publisher: Springer Science & Business Media

ISBN: 1617799831

Category: Science

Page: 538

View: 934

Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Second Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive first edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as nanodiagnostics and nanopharmaceuticals, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Second Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.

Chemicals in the Environment

Assessing and Managing Risk

Author: Ronald E. Hester,R. M. Harrison,Royal Society of Chemistry (Great Britain)

Publisher: Royal Society of Chemistry

ISBN: 0854042067

Category: Law

Page: 158

View: 9164

Reviews the contemporary framework of legislation for the regulation of chemicals in the UK ...

Nanotechnology in the Agri-Food Sector

Implications for the Future

Author: Lynn J. Frewer,Willem Norde,Arnout Fischer,Frans Kampers

Publisher: John Wiley & Sons

ISBN: 9783527634804

Category: Technology & Engineering

Page: 328

View: 9483

Providing an overview of nanotechnology in the context of agriculture and food science, this monograph covers topics such as nano-applications in teh agri-food sector, as well as the social and ethical implications. Following a review of the basics, the book goes on to take an in-depth look at processing and engineering, encapsulation and delivery, packaging, crop protection and disease. It highlights the technical, regulatory, and safety aspects of nanotechnology in food science and agriculture, while also considering the environmental impact. A valuable and accessible guide for professionals, novices, and students alike.

Research on environmental and safety impacts of nanotechnology

current status of planning and implementation under the National Nanotechnology Initiative : hearing before the Subcommittee on Research and Science Education, Committee on Science and Technology, House of Representatives, One Hundred Tenth Congress, first session, October 31, 2007

Author: United States. Congress. House. Committee on Science and Technology (2007). Subcommittee on Research and Science Education

Publisher: N.A

ISBN: N.A

Category: Technology & Engineering

Page: 140

View: 3961

Nanoneuroscience and Nanoneuropharmacology

Author: Hari S. Sharma

Publisher: Elsevier

ISBN: 9780080962245

Category: Science

Page: 264

View: 9212

This volume presents articles from the leading experts in the field in nanobiotechnology, providing students and researchers with a comprehensive review of the newly emerging area of neuroscience. All aspects of nanomaterials induced alteration in brain function are considered. Basic chapters on methods and ways to enhance nano-drug delivery into the brain are presented as well as chapters on functional and structural changes in the CNS, including gene expression and related issues. Particular attention is given to possible therapeutic advancement regarding nano-drug formulation and their role in neuroprotection.

Find eBook