Organic chemistry is not merely a compilation of principles, but rather, it is a disciplined method of thought and analysis. Success in organic chemistry requires mastery in two core aspects: fundamental concepts and the skills needed to apply those concepts and solve problems. Readers must learn to become proficient at approaching new situations methodically, based on a repertoire of skills. These skills are vital for successful problem solving in organic chemistry. Existing textbooks provide extensive coverage of, the principles, but there is far less emphasis on the skills needed to actually solve problems.
Fundamentals of General, Organic, and Biological Chemistry
Author: Prentice Hall-Pearson Education, Inc
John McMurry, educated at Harvard and Columbia, has taught approximately 17,000 students in general and organic chemistry over a 30-year period. AProfessor of Chemistry at Cornell University since 1980, Dr. McMurry previously spent 13 years on the faculty at the University of California at Santa Cruz. He has received numerous awards, including the Alfred P. Sloan Fellowship (1969 71), the National Institute of Health Career Development Award (1975 80), the Alexander von Humboldt Senior Scientist Award (1986 87), and the Max Planck Research Award (1991). About the Authors David S. Ballantine received his B.S. in Chemistry in 1977 from the College of William and Mary in Williamsburg, VA, and his Ph.D. in Chemistry in 1983 from the University of Maryland at College Park. After several years as a researcher at the Naval Research Labs in Washington, DC, he joined the faculty in the Department of Chemistry and Biochemistry of Northern Illinois University, where he has been a professor for the past twenty years. He was awarded the Excellence in Undergraduate Teaching Award in 1998 and was recently named the departmental Director of Undergraduate Studies. In addition, he is the faculty advisor to the NIU Chemistry Club, an American Chemical Society Student Affiliate program. Carl A.Hoeger received his B.S. in Chemistry from San Diego State University and his Ph.D. in Organic Chemistry from the University of Wisconsin, Madison in 1983. After a postdoctoral stint at the University of California, Riverside, he joined the Peptide Biology Laboratory at the Salk Institute in 1985 where he ran the NIH Peptide Facility while doing basic research in the development of peptide agonists and antagonists. During this time he also taught general, organic, and biochemistry at San Diego City College, Palomar College, and Miramar College. He joined the teaching faculty at University of Califiornia, San Diego in 1998. Dr. Hoeger has been teaching chemistry to undergraduates for over 20 years, where he continues to explore the use of technology in the classroom. In 2004 he won the Paul and Barbara Saltman Distinguished Teaching Award from UCSD. He is currently the General Chemistry coordinator at UCSD, where he is also responsible for the training and guidance of over 100 teaching assistants in the Chemistry and Biochemistry departments. Virginia E. Peterson received her B.S. in Chemistry in 1967 from the University of Washington in Seattle, and her Ph.D. in Biochemistry in 1980 from the University of Maryland at College Park. Between her undergraduate and graduate years she worked in lipid, diabetes, and heart disease research at Stanford University. Following her Ph.D. she took a position in the Biochemistry Department at the University of Missouri in Columbia and is now an Associate Professor. Currently she is the Director of Undergraduate Advising for the department and teaches both senior capstone classes and biochemistry classes for nonscience majors. Awards include both the college level and the university-wide Excellence in Teaching Award and, in 2006, the University s Outstanding Advisor Award and the State of Missouri Outstanding University Advisor Award. Dr. Peterson believes in public service and in 2003 received the Silver Beaver Award for service from the Boy Scouts of America. This textbook is primarily designed to provide students in the allied health sciences with an appropriate background in chemistry and biochemistry. But it also provides a general context for many of the chemical concepts so that students in other disciplines will gain a better appreciation of the importance of chemistry in everyday life. The coverage in this sixth edition includes sufficient breadth and depth to ensure adequate context and to provide students with opportunities to expand their knowledge. To teach chemistry all the way from What is an atom? to How do we get energy from glucose? is a challenge. Throughout our general chemistry and organic chemistry coverage, the focus is on concepts fundamental to the chemistry of living things and everyday life. In our biochemistry coverage we strive to meet the further challenge of providing a context for the application of those concepts in biological systems. Our goal is to provide enough detail for thorough understanding while avoiding so much detail that students are overwhelmed. Many practical and relevant examples are included to illustrate the concepts and enhance student learning. The material covered is ample for a two-term introduction to general, organic, and biological chemistry. While the general and early organic chapters contain concepts that are fundamental to understanding the material in biochemistry, the later chapters can be covered individually and in an order that can be adjusted to meet the needs of the students and the duration of the course. The writing style is clear and concise and punctuated with practical and familiar examples from students personal experience. Art work, diagrams, and molecular models are used extensively to provide graphical illustration of concepts to enhance student understanding. Since the true test of knowledge is the ability to apply that knowledge appropriately, we include numerous worked examples that incorporate consistent problem-solving strategies. Regardless of their career paths, all students will be citizens in an increasingly technological society. When they recognize the principles of chemistry at work not just in their careers but in their daily lives, they are prepared to make informed decisions on scientific issues based on a firm understanding of the underlying concepts. Organization GENERAL CHEMISTRY: CHAPTERS 1 11 The introduction to elements, atoms, the periodic table, and the quantitative nature of chemistry (Chapters 1 3) is followed by chapters that individually highlight the nature of ionic and molecular compounds (Chapters 4 and 5). The next two chapters discuss chemical reactions and their stoichiometry, energies, rates, and equilibria (Chapters 6 and 7). Topics relevant to the chemistry of life follow: Gases, Liquids, and Solids (Chapter 8); Solutions (Chapter 9); and Acids and Bases (Chapter 10). Nuclear Chemistry (Chapter 11) closes the general chemistry sequence. ORGANIC CHEMISTRY: CHAPTERS 12 17 These chapters concisely focus on what students must know in order to understand biochemistry. The introduction to hydrocarbons (Chapters 12 and 13) includes the basics of nomenclature, which is thereafter kept to a minimum. Discussion of functional groups with single bonds to oxygen, sulfur, or a halogen (Chapter 14) is followed by a short chapter on amines, which are so important to the chemistry of living things and drugs (Chapter 15). After introducing aldehydes and ketones (Chapter 16), the chemistry of carboxylic acids and their derivatives (including amides) is covered (Chapter 17), with a focus on similarities among the derivatives. xv Preface BIOLOGICAL CHEMISTRY: CHAPTERS 18 29 Rather than proceed through the complexities of protein, carbohydrate, lipid, and nucleic acid structure before getting to the roles of these compounds in the body, structure and function are integrated in this text. Protein structure (Chapter 18) is followed by enzyme and coenzyme chemistry (Chapter 19). After that we cover the function of hormones and neurotransmitters, and the action of drugs (Chapter 20). With enzymes introduced, the central pathways and themes of biochemical energy production can be described (Chapter 21). If the time you have available to cover biochemistry is limited, stop with Chapter 21 and your students will have an excellent preparation in the essentials of metabolism. The following chapters cover carbohydrate chemistry (Chapters 22 and 23), then lipid chemistry (Chapters 24 and 25). Next we discuss nucleic acids and protein synthesis (Chapter 26) and genomics (Chapter 27). The last two chapters cover protein and amino acid metabolism (Chapter 28) and provide an overview of the chemistry of body fluids (Chapter 29). Changes to This Edition COVERAGE OF GENERAL CHEMISTRY Once again, there is a major emphasis in this edition on problem-solving strategies. This is reflected in expanded solutions in the Worked Example problems and the addition of more Key Concept Problems that focus on conceptual understanding. The most significant change in the Worked Example problems is the addition of a Ballpark Estimate at the beginning of many problems. The Ballpark Estimate provides an opportunity for students to evaluate the relationships involved in the problem and allows them to use an intuitive approach to arrive at a first approximation of the final answer. The ability to think through a problem before attempting a mathematical solution is a skill that will be particularly useful on exams, or when solving real world problems. Other specific changes to chapters are provided below: Chapter 1 The Scientific Method is introduced in the text and reinforced in Applications presented in the chapter. Chapter 3 Discussion of the critical experiments of Thomson, Millikan, and Rutherford are included in the Application Are Atoms Real to provide historical perspective on the development of our understanding of atomic structure. Electron dot structures are introduced in Chapter 3 to emphasize the importance of the valence shell electronic configurations with respect to chemical behavior of the elements. Chapter 4 Electron dot structures are used to reinforce the role of valence shell electronic configurations in explaining periodic behavior and the formation of ions. Chapter 5 The two methods for drawing Lewis dot structures (the general method and the streamlined method for molecules containing C, N, O, X, and H) are discussed back-to-back to highlight the underlying principle of the octet rule common to both methods. Chapter 6 The concept of limiting reagents is incorporated in Section 6.7 in the discussion of reaction stoichiometry and percent yields. xvi Preface Chapter 7 The discussion of free energy and entropy in Section 7.4 has been revised to help students develop a more intuitive understanding of the role of entropy in spontaneous processes. Section 7.8 includes more discussion of how the equilibrium constant is calculated and what it tells us about the extent of reaction. Chapter 8 Sections 8.3 8.10 include more emphasis on use of the kinetic molecular theory to understand the behavior of gases described by the gas laws. Section 8.15 includes more discussion on the energetics of phase changes to help students understand the difference between heat transfer associated with a temperature change and heat transfer associated with the phase change of a substance. Chapter 9 Discussion of equivalents in Section 9.10 has been revised to emphasize the relationship between ionic charge and equivalents of ionic compounds. Discussion of osmotic pressure (Section 9.12) now includes the osmotic pressure equation and emphasizes the similarity with the ideal gas law. Chapter 10 Both the algebraic and logarithmic forms of K w are presented in Section 10.8 to give students another approach to solving pH problems. The discussion of buffer systems now introduces the Henderson-Hasselbalch equation. This relationship makes it easier to identify the factors that affect the pH of a buffer system and is particularly useful in biochemical applications in later chapters. Discussion of common acid-base reactions has been moved back in the chapter to provide a more logical segue into titrations in Section 10.15. Chapter 11 Treatment of half-life in Section 11.5 now includes a generic equation to allow students to determine the fraction of isotope remaining after an integral or non-integral number of half-lives, which is more consistent with real world applications. The Applications in this chapter have been expanded to include discussion of new technologies such as Boron Neutron-Capture Therapy (BNCT), or to clear up misconceptions about current methods such as MRI. COVERAGE OF ORGANIC CHEMISTRY Amajor emphasis in this edition was placed on making the fundamental reactions organic molecules undergo much clearer to the reader, with particular vision toward those reactions encountered again in biochemical transformations. Also new to this edition is the expanded use and evaluation of line-angle structure for organic molecules, which are so important when discussing biomolecules. Most of the Applications have been updated to reflect current understanding and research. Other specific changes to chapters are provided below: Chapter 12 This chapter has been significantly rewritten to provide the student with a stronger foundation for the organic chemistry chapters that follow. Aclearer description of what a functional group is, as well as a more systematic approach to drawing alkane isomers have been made. Preface xvii The topic of how to draw and interpret line structures for organic molecules has been added, along with worked examples of such. The discussion of conformations has been expanded. Chapter 13 Amore general discussion of cis and trans isomers has been added. The discussion of organic reaction types, particularly rearrangement reactions, have been simplified. Chapter 14 The topic of oxidation in organic molecules has been clarified. Chapter 15 The role of NO in human biology has been updated to reflect current research. Chapter 16 A more detailed discussion of what is meant by toxic or poisonous has been added. Chapter 17 Adiscussion of ibuprofen has been added. COVERAGE OF BIOLOGICAL CHEMISTRY New topics, such as the use of anabolic steroids in sports, have been added to many of these chapters to highlight the relevance of biochemistry in modern society. In this text, nutrition is not treated as a separate subject but is integrated with the discussion of each type of biomolecule. Chapter 18 The discussion of sickle cell anemia has been expanded and the role of an amino acid substitution on hemoglobin structure clarified. The Application Prions Proteins That Cause Disease has been updated to reflect current research. Chapter 19 Incorporated the information about lead poisoning into the discussion of enzyme inhibition. Chapter 20 The discussion of anabolic steroids has been updated. The discussion of drugs and their interaction with the neurotransmitter acetylcholine has been expanded. Chapter 21 The discussion of ATP energy production has been revised. Chapter 22 An explanation of the chair conformation of glucose has been included to enhance understanding of the shape of cyclic sugars. The Application Chirality and Drugs has been updated. The Application Cell Surface Carbohydrates and Blood Type has been revised. xviii Preface Chapter 23 The explanation of substrate level phosphorylation has been expanded for clarity. The emerging medical condition referred to as Metabolic Syndrome has been added to the text discussion of diabetes. The Application Diagnosis and Monitoring of Diabetes has been updated to include metabolic syndrome. Section 23.11 now contains an expanded discussion of gluconeogenesis. The discussion of polysaccharides has been updated. Chapter 24 The description of the cell membrane has been expanded. A discussion of some inhibitors of Cox 1 and Cox 2 enzymes, important in inflammation, has been added. Chapter 25 The discussion of triacylglycerol synthesis has been expanded. The discussion of ketone body formation has been expanded. A thorough explanation of the biosynthesis of fatty acids has been added. Chapter 26 The Application Viruses and AIDS has been updated. Information about the 1918 influenza pandemic was included in the Application Bird Flu : The Next Epidemic? Chapter 27 A discussion of the problems associated with using recombinant DNA for commercial protein manufacture has been added. In Section 27.5, new bioethical issues are pointed out to reflect modern concerns. The discussion of recombinant DNA and polymerase chain reactions has been moved to this chapter from Chapter 26. Focus on Learning WORKED EXAMPLES Most Worked Examples, both quantitative and not quantitative, include an Analysis section that precedes the Solution. The Analysis lays out the approach to solving a problem of the given type. When appropriate, a Ballpark Estimate gives students an overview of the relationships needed to solve the problem, and provides an intuitive approach to arrive at a rough estimate of the answer. The Solution presents the worked-out example using the strategy laid out in the Analysis and, in many cases, includes expanded discussion to enhance student understanding. The use of the two-column format introduced in the fifth edition for quantitative problems has been applied to more Worked Examples throughout the text. Following the Solution there is a Ballpark Check that compares the calculated answer to the Ballpark Estimate, when appropriate, and verifies that the answer makes chemical and physical sense. KEY CONCEPT PROBLEMS are integrated throughout the chapters to focus attention on the use of essential concepts, as do the Understanding Key Concepts problems at the end of each chapter. Understanding Key Concepts problems are designed to test students mastery of the core principles developed in the chapter. Students thus Preface xix have an opportunity to ask Did I get it? before they proceed. Most of these Key Concept Problems use graphics or molecular-level art to illustrate the core principles and will be particularly useful to visual learners. PROBLEMS The problems within the chapters, for which brief answers are given in an appendix, cover every skill and topic to be understood. One or more problems, many of which are new to this edition, follow each Worked Example and others stand alone at the ends of sections. MORE COLOR-KEYED, LABELED EQUATIONS It is entirely too easy to skip looking at a chemical equation while reading. We have extensively used color to call attention to the aspects of chemical equations and structures under discussion, a continuing feature of this book that has been judged very helpful. MOLECULAR MODELS Additional computer-generated molecular models have been introduced, including the use of electrostatic-potential maps for molecular models. KEY WORDS Every key term is boldfaced on its first use, fully defined in the margin adjacent to that use, and listed at the end of the chapter. These are the terms students must understand to get on with the subject at hand. Definitions of all Key Words are collected in the Glossary. END-OF-CHAPTER SUMMARIES Here, the answers to the questions posed at the beginning of the chapter provide a summary of what is covered in that chapter. Where appropriate, the types of chemical reactions in a chapter are also summarized. Focus on Relevancy Chemistry is often considered to be a difficult and tedious subject. But when students make a connection between a concept in class and an application in their daily lives the chemistry comes alive, and they get excited about the subject. The applications in this book strive to capture student interest and emphasize the relevance of the scientific concepts. The use of relevant applications makes the concepts more accessible and increases understanding. Applications are both integrated into the discussions in the text and set off from the text in Application boxes. Each boxed application provides sufficient information for reasonable understanding and, in many cases, extends the concepts discussed in the text in new ways. The boxes end with a cross-reference to end-of-chapter problems that can be assigned by the instructor. Some wellreceived Applications from previous editions that have been retained include Breathing and Oxygen Transport, Buffers in the Body, Prions, Protein Analysis by Electrophoresis, The Biochemistry of Running, and DNA Fingerprinting. New Applications in this edition include Aspirin A Case Study, Temperature- Sensitive Materials, Anemia A Limiting Reagent Problem, GERD: Too Much Acid or Not Enough, and It s a Ribozyme! FOCUS ON MAKING CONNECTIONS AMONG GENERAL, ORGANIC, AND BIOLOGICAL CHEMISTRY This can be a difficult course to teach. Much of what students are interested in lies in the last part of the course, but the material they need to understand the biochemistry is found in the first two-thirds. It is easy to lose sight of the connections among general, organic, and biological chemistry so we use a feature, Concepts to Review, to call attention to these connections. From Chapter 4 on, the Concepts to Review section at the beginning of the chapter lists topics covered in earlier chapters that form the basis for what is discussed in the current chapter. xx Preface We have also retained the successful concept link icons and Looking Ahead notes. Concept link icons are used extensively to indicate places where previously covered material is relevant to the discussion at hand. These links provide for cross-references and also serve to highlight important chemical themes as they are revisited. Looking Ahead notes call attention to connections between just-covered material and discussions in forthcoming chapters. These notes are designed to illustrate to the students why what they are learning will be useful in what lies ahead. Making It Easier to Teach: Supplements for Instructors MasteringChemistry (www.masteringchemistry.com) MasteringChemistry is the first adaptive-learning online homework system. It provides selected end-of-chapter problems from the text, as well as hundreds of tutorials with automatic grading, immediate answer-specific feedback, and simpler questions on request. Based on extensive research of precise concepts students struggle with, MasteringChemistry uniquely responds to your immediate needs, thereby optimizing your study time. Instructor Resource Manual (0-32-161241-8) Features lecture outlines with presentation suggestions, teaching tips, suggested in-class demonstrations, and topics for classroom discussion. Test Item File (0-32-161514-X) Updated to reflect the revisions in this text and contains questions in a bank of more than 2,000 multiple-choice questions. Transparency Pack (0-32-161513-1) More than 225 full-color transparencies chosen from the text put principles into visual perspective and save you time while you are preparing for your lectures. Instructor Resource Center on CD/DVD (0-32-161242-6) This CD/DVD provides an intergrated collection of resources designed to help you make efficient and effective use of your time. This CD/DVD features most art from the text, including figures and tables in PDF format for high-resolution printing, as well as four pre-built PowerPoint presentations. The first presentation contains the images/ figures/tables embedded within the PowerPoint slides, while the second includes a complete modifiable lecture outline. The final two presentations contain worked in chapter sample exercises and questions to be used with Classroom Response Systems. This CD/DVD also contains movies and animations, as well as the TestGen version of the Test Item File, which allows you to create and tailor exams to your needs. BlackBoard® and WebCT® Practice and assessment materials are available upon request in these course management platforms. Making It Easier to Learn: Supplements for Students Study Guide and Full Solutions Manual (0-32-161238-8) and Study Guide and Selected Solutions Manual (0-32-161239-6), both by Susan McMurry. The selected version provides solutions only to those problems that have a short answer in the Preface xxi text s Selected Answer Appendix (problems numbered in blue in the text). Both versions explain in detail how the answers to the in-text and end-of-chapter problems are obtained. They also contain chapter summaries, study hints, and self-tests for each chapter. For the Laboratory Exploring Chemistry: Laboratory Experiments in General, Organic and Biological Chemistry, 2nd Edition (0-13-047714-1) by Julie R. Peller of Indiana University. Written specifically to accompany Fundamentals of General, Organic and Biological Chemistry, this manual contains 34 fresh and accessible experiments specifically for GOB students. Catalyst: The Prentice Hall Custom Laboratory Program for Chemistry. This program allows you to custom-build a chemistry lab manual that matches your content needs and course organization. You can either write your own labs using the Lab Authoring Kit tool, or select from the hundreds of labs available at www. prenhall.com/catalyst. This program also allows you to add your own course notes, syllabi, or other materials. Acknowledgments From conception to completion, the development of a modern textbook requires both a focused attention on the goals and the coordinated efforts of a diverse team. We have been most fortunate to have had the services of many talented and dedicated individuals whose efforts have contributed greatly to the overall quality of this text. First and foremost, we are grateful to Kent Porter Hamann who, as senior editor of this text through many past revisions, provided exemplary leadership and encouragement to the team in the early stages of this project. Very special appreciation goes to Ray Mullaney, editor in chief of book development, who mentored the new team members and managed to coordinate the many and varied details. Irene Nunes, our developmental editor, worked closely with the authors to ensure accuracy and consistency. We also are grateful for the services of Wendy Perez, project manager; Laurie Varites, assistant editor; Lia Tarabokjia, and Jill Traut and Robert Walters, production project managers. Finally, special thanks also to Susan McMurry and Margaret Trombley, whose efforts on the Solutions Manuals and MasteringChemistry tutorial software, respectively, have added value to the overall package. Finally, many instructors and students who have used the fifth edition have provided valuable insights and feedback and improved the accuracy of the current edition. We gratefully acknowledge the following reviewers for their contributions to the sixth edition: xxii Preface Sheikh Ahmed, West Virgina University Stanley Bajue, CUNY-Medgar Evers College Daniel Bender, Sacramento City College Dianne A. Bennett, Sacramento City College Alfredo Castro, Felician College Gezahegn Chaka, Louisiana State University, Alexandria Michael Columbia, Indiana University- Purdue University, Fort Wayne Rajeev B. Dabke, Columbus State University Danae R. Quirk-Dorr, Minnesota State University, Mankato Pamela S. Doyle, Essex County College Marie E. Dunstan, York College of Pennsylvania Karen L. Ericson, Indiana University-Purdue University, Fort Wayne Charles P. Gibson, University of Wisconsin, Oshkosh Clifford Gottlieb, Shasta College Mildred V. Hall, Clark State Community College Meg Hausman, University of Southern Maine Ronald Hirko, South Dakota State University L. Jaye Hopkins, Spokane Community College Margaret Isbell, Sacramento City College James T. Johnson, Sinclair Community College Margaret G. Kimble, Indiana University- Purdue University Fort Wayne Preface xxiii Grace Lasker, Lake Washington Technical College Ashley Mahoney, Bethel University Matthew G. Marmorino, Indiana University, South Bend Diann Marten, South Central College, Mankato Barbara D. Mowery, York College of Pennsylvania Tracey Arnold Murray, Capital University Andrew M. Napper, Shawnee State University Lisa Nichols, Butte Community College Glenn S. Nomura, Georgia Perimeter College Douglas E. Raynie, South Dakota State University Paul D. Root, Henry Ford Community College Victor V. Ryzhov, Northern Illinois University Karen Sanchez, Florida Community College, Jacksonville-South Mir Shamsuddin, Loyola University, Chicago Jeanne A. Stuckey, University of Michigan John Sullivan, Highland Community College Deborah E. Swain, North Carolina Central University Susan T. Thomas, University of Texas, San Antonio Yakov Woldman, Valdosta State University The authors are committed to maintaining the highest quality and accuracy and look forward to comments from students and instructors regarding any aspect of this text and supporting materials. Questions or comments should be directed to the lead co-author. David S. Ballantine [email protected]
Pollutants, Human Health and the Environment is a comprehensive, up-to-date overview of environmental pollutants that are of current concern to human health. Clearly structured throughout, the main body of the book is divided by pollutant type with a chapter devoted to each group of pollutants. Each chapter follows a similar format to facilitate comparison and discussion. For each pollutant, the authors describe the sources, pathways, environmental fate and sinks as well as known toxicological effects. Importantly, the second chapter on heavy metals and other inorganic substances deals with trace element deficiencies which can have serious problems for human health. Some rocks and soils are naturally low in some trace elements and intensive agriculture over the past half century has effectively mined many trace elements reducing their levels in soils and crops. The final chapter is a discussion about the various risk assessment frameworks and regulations covering the main pollutants. Comprehensive, up-to-date coverage of environmental pollutants of concern to human health Clearly divided into pollutant type with each chapter devoted to a different pollutant group Clearly structured throughout with the same format for each chapter to help facilitate comparison and discussion and enable readers to prioritise chemicals of concern Description of the sources, pathways, environmental fate and known toxicological effect Includes contributions from leading researchers and edited by a team of experts in the field
Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants. • Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds • Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants • Expands on each chapter from the first edition with additional data and updated discussion from recent findings • "The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010
"General Chemistry: Atoms First," Second Edition starts from the building blocks of chemistry, the atom, allowing the authors to tell a cohesive story that progresses logically through molecules and compounds to help students intuitively follow complex concepts more logically. This unified thread of ideas helps students build a better foundation and ultimately gain a deeper understanding of chemical concepts. Students can more easily understand the microscopic-to-macroscopic connections between unobservable atoms and the observable behavior of matter in daily life, and are brought immediately into real chemistryinstead of being forced to memorize facts. Reflecting a true atoms first perspective, the Second Edition features experienced atoms-first authors, incorporates recommendations from a panel of atoms-first experts, and follows historical beliefs in teaching chemistry concepts based and real experimental data first. This approach distinguishes this text in the market based whereby other authors teach theory first, followed by experimental data.
Green Chemistry: An Inclusive Approach provides a broad overview of green chemistry for researchers from either an environmental science or chemistry background, starting at a more elementary level, incorporating more advanced concepts, and including more chemistry as the book progresses. Every chapter includes recent, state-of-the-art references, in particular, review articles, to introduce researchers to this field of interest and provide them with information that can be easily built upon. By bringing together experts in multiple subdisciplines of green chemistry, the editors have curated a single central resource for an introduction to the discipline as a whole. Topics include a broad array of research fields, including the chemistry of Earth’s atmosphere, water and soil, the synthesis of fine chemicals, and sections on pharmaceuticals, plastics, energy related issues (energy storage, fuel cells, solar, and wind energy conversion etc., greenhouse gases and their handling, chemical toxicology issues of everyday products (from perfumes to detergents or clothing), and environmental policy issues. Introduces the topic of green chemistry with an overview of key concepts Expands upon presented concepts with the latest research and applications, providing both the breadth and depth researchers need Includes a broad range of application based problems to make the content accessible for professional researchers and undergraduate and graduate students Authored by experts in a broad range of fields, providing insider information on the aspects or challenges of a given field that are most important and urgent
Finally, a stand-alone, all-inclusive textbook on yeast biology. Based on the feedback resulting from his highly successful monograph, Horst Feldmann has totally rewritten he contents to produce a comprehensive, student-friendly textbook on the topic. The scope has been widened, with almost double the content so as to include all aspects of yeast biology, from genetics via cell biology right up to biotechnology applications. The cell and molecular biology sections have been vastly expanded, while information on other yeast species has been added, with contributions from additional authors. Naturally, the illustrations are in full color throughout, and the book is backed by a complimentary website. The resulting textbook caters to the needs of an increasing number of students in biomedical research, cell and molecular biology, microbiology and biotechnology who end up using yeast as an important tool or model organism.