Search Results: toxoplasma-gondii-the-model-apicomplexan-perspectives-and-methods

Toxoplasma Gondii

The Model Apicomplexan - Perspectives and Methods

Author: Louis M. Weiss,Kami Kim

Publisher: Academic Press

ISBN: 0123965365

Category: Science

Page: 1160

View: 7100

This 2e of Toxoplasma gondii reflects the significant advances in the field in the last 5 years, including new information on the genomics, epigenomics and proteomics of T. gondii as well as a new understanding of the population biology and genetic diversity of this organism. T. gondii remains the best model system for studying the entire Apicomplexa group of protozoans, which includes Malaria, making this new edition essential for a broad group of researchers and scientists. Toxoplasmosis is caused by a one-celled protozoan parasite known as T. gondii. The infection produces a wide range of clinical syndromes in humans, land and sea mammals, and various bird species. Most humans contract toxoplasmosis by eating contaminated, raw or undercooked meat (particularly pork), vegetables, or milk products; by coming into contact with the T. gondii eggs from cat feces; or by drinking contaminated water. The parasite damages the ocular and central nervous systems, causing behavioral and personality alterations as well as fatal necrotizing encephalitis. It is especially dangerous for the fetus of an infected pregnant woman and for individuals with compromised immune systems, such as HIV-infected patients. Completely updated, the 2e presents recent advances driven by new information on the genetics and genomics of the pathogen Provides the latest information concerning the epidemiology, diagnosis, treatment and prevention of toxoplasmosis Offers a single-source reference for a wide range of scientists and physicians working with this pathogen, including parasitologists, cell and molecular biologists, veterinarians, neuroscientists, physicians, and food scientists

Foodborne Parasites in the Food Supply Web

Occurrence and Control

Author: Alvin A Gajadhar

Publisher: Woodhead Publishing

ISBN: 1782423508

Category: Technology & Engineering

Page: 482

View: 7953

Foodborne Parasites in the Food Supply Web: Occurrence and Control provides an overview of the occurrence, transmission, and control of parasites in the food chain, including an introduction to the topic from the perspectives of various issues surrounding foodborne parasites. The text then explores the different types of foodborne parasites, the dynamics of parasite transmission in different food sources, and the prevention and control of foodborne parasites in the food chain. Provides an overview of the occurrence, transmission, and control of parasites in the food chain Explores the different types of foodborne parasites and the dynamics of parasite transmission in different food sources Highlights prevention and control methods to ensure the safety of the food chain

Molecular Detection of Human Parasitic Pathogens

Author: Dongyou Liu

Publisher: CRC Press

ISBN: 1439812438

Category: Medical

Page: 895

View: 2811

Traditionally, laboratory identification of parasites has relied upon various phenotypic procedures that detect their morphological, biological, and immunological features. Because these procedures tend to be time-consuming and technically demanding, molecular methods based on nucleic acid amplification technologies have been increasingly utilized for rapid, sensitive, and specific characterization of parasites. The large number of original and modified molecular protocols that have been developed over the years creates a dilemma for those attempting to adopt the most appropriate protocol for streamlined identification and detection of human pathogenic organisms of interest. Part of a four-volume collection, Molecular Detection of Human Parasitic Pathogens provides a reliable and comprehensive resource on the molecular detection and identification of major human parasitic pathogens. This volume contains expert contributions from international scientists involved in human parasitic pathogen research and diagnosis. Following a similar format throughout, each chapter includes: A brief review on the classification, biology, epidemiology, clinical features, and diagnosis of an important pathogenic parasitic genus/group An outline of clinical sample collection and preparation procedures and a selection of representative stepwise molecular protocols A discussion on further research needs relating to improved diagnoses of major human parasitic pathogens This versatile reference on molecular detection and identification of major human parasitic pathogens is an indispensable tool for upcoming and experienced medical, veterinary, and industrial laboratory scientists engaged in parasite characterization. It is also suitable as a textbook for undergraduate and graduate students majoring in parasitology.

Toxoplasmosis of Animals and Humans, Second Edition

Author: J. P. Dubey

Publisher: CRC Press

ISBN: 9781420092370

Category: Science

Page: 336

View: 1294

Found worldwide from Alaska to Australasia, Toxoplasma gondii knows no geographic boundaries. The protozoan is the source of one of the most common parasitic infections in humans, livestock, companion animals, and wildlife, and has gained notoriety with its inclusion on the list of potential bioterrorism microbes. In the two decades since the publication of the first edition of Toxoplasmosis of Animals and Humans there has been an explosion of knowledge concerning T. gondii and toxoplasmosis. Still used extensively as a cell model, its genome has recently been published making it a subject of even greater scientific interest. Keeping the organizational style that made the previous edition so popular and usable, this second edition has been completely revised and updated. New in the Second Edition: Expanded information on the cultivation, maintenance, and preservation of T. gondii Expanded information on the cell biology and molecular biology of the parasite Reviews all literature from the past 20 years for each domestic animal Summarizes information on the worldwide prevalence of toxoplasmosis in pregnant women and the devastating disease it can cause in newborn Written by one of the pioneers of the field, the book provides unique information on all known host types for this parasite. It distills the voluminous and potentially confusing scientific literature that has grown geometrically in the 20 years since the publication of the first edition into a comprehensive resource. The single author approach ensures a strong foundation in the biology and a seamless integration of topics. The new edition of this groundbreaking work is the only volume to cover toxoplasmosis of animals and humans thoroughly in one source. It supplies an entry point to further research by cutting through the morass of literature to identify the most relevant references.

People, Parasites, and Plowshares

Learning From Our Body's Most Terrifying Invaders

Author: Dickson Despommier

Publisher: Columbia University Press

ISBN: 0231161948

Category: Medical

Page: 208

View: 9995

An account of the biology, behavior, and history of parasites, following the interplay between these fascinating life forms and human society over thousands of years. Despommier focuses on long-term host-parasite associations, which have evolved to avoid or even subvert the human immune system.

Parasitic Zoonoses

Author: B.B.Singh Dhaliwal,Prayag Dutt Juyal

Publisher: Springer Science & Business Media

ISBN: 8132215516

Category: Science

Page: 135

View: 6894

The book “Parasitic Zoonoses” emphasizes a veterinary and public health perspective of zoonotic parasites. This book is suitable for higher undergraduate and graduate students of zoonoses and public health, veterinary parasitology, parasite epidemiology; public health workers; public health veterinarians; field veterinarians, medical professionals and all others interested in the subject. More than 15 protozoa and 50 other parasitic diseases are zoonotic in nature and all these diseases have been discussed in detail. The first chapter is concerned with classification of zoonotic parasites, food borne, vector borne and occupation related zoonotic parasites. The remaining chapters cover etiology, epidemiology, life cycle, transmission, clinical signs, diagnosis, prevention and control of zoonotic parasites. The text is illustrated with a large number of coloured figures. An alphabetical bibliography for every disease has also been included so that readers have access to further information.

Animal Waste, Water Quality and Human Health

Author: Al Dufour

Publisher: IWA Publishing

ISBN: 178040123X

Category: Science

Page: 476

View: 7610

"United States, Environmental Protection Agency."

Toxoplasma

Molecular and Cellular Biology

Author: Dominique Soldati

Publisher: Horizon Scientific Press

ISBN: 1904933343

Category: Science

Page: 625

View: 6855

Toxoplasma gondii, once an obscure protozoan parasite, has recently become the focus of intense research, both as a serious pathogen in its own right and as a model member of the phylum Apicomplexa. Written by internationally acclaimed researchers, this is the first book to provide a comprehensive coverage of this important parasite from both the host and pathogen perspectives. The authors of this book describe in detail the biological characteristics that make T. gondii and related apicomplexans the most common and successful group of parasites on earth. Essential reading for all researchers working with Toxoplasma and related apicomplexans, Plasmodium, Cryptosporidium, and other protozoan parasites.

Structures and Organelles in Pathogenic Protists

Author: W. de Souza

Publisher: Springer Science & Business Media

ISBN: 9783642128639

Category: Science

Page: 324

View: 7679

Parasitic protozoa, including some which are agents of human and veterinary diseases, display special cytoplasmic structures and organelles. Metabolic pathways have been discovered in these organelles which open up new possibilities for drug targets. This work presents reviews dealing with cytoskeletal structures such as the mastigont system found in trichomonads, the sub-pellicular microtubules in trypanosomatids and the paraflagellar rod. Further chapters cover structures involved in the synthesis, secretion and uptake of molecules, including the flagellar pocket of trypanosomatids, the reservosome of Trypanosoma and the megasome found in Leishmania, the traffic of vesicles in Entamoeba histolytica, secretory organelles and the secretory events of intestinal parasites during encystation. Reviews on special organelles, such as the kinetoplast-mitochondrion complex, the apicoplast found in Apicomplexa, the glycosomes in Kinetoplastida and the acidocalcisomes found in several protozoa complete the volume.

The Evolution of the Immune System

Conservation and Diversification

Author: Davide Malagoli

Publisher: Academic Press

ISBN: 012802013X

Category: Medical

Page: 384

View: 6514

The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership

Assembling the Tree of Life

Author: Joel Cracraft,Michael J. Donoghue

Publisher: Oxford University Press

ISBN: 9780199729609

Category: Science

Page: 592

View: 2030

This edited volume is provides an authoritative synthesis of knowledge about the history of life. All the major groups of organisms are treated, by the leading workers in their fields. With sections on: The Importance of Knowing the Tree of Life; The Origin and Radiation of Life on Earth; The Relationships of Green Plants; The Relationships of Fungi; and The Relationships of Animals. This book should prove indispensable for evolutionary biologists, taxonomists, ecologists interested in biodiversity, and as a baseline sourcebook for organismic biologists, botanists, and microbiologists. An essential reference in this fundamental area.

The Produce Contamination Problem

Causes and Solutions

Author: Karl R. Matthews,Gerald M. Sapers,Charles P. Gerba

Publisher: Academic Press

ISBN: 012404686X

Category: Technology & Engineering

Page: 492

View: 3449

Understanding the causes and contributing factors leading to outbreaks of food-borne illness associated with contamination of fresh produce is a worldwide challenge for everyone from the growers of fresh-cut produce through the entire production and delivery process. The premise of The Produce Contamination Problem is that when human pathogen contamination of fresh produce occurs, it is extremely difficult to reduce pathogen levels sufficiently to assure microbiological safety with the currently available technologies. A wiser strategy would be to avoid crop production conditions that result in microbial contamination to start. These critical, problem-oriented chapters have been written by researchers active in the areas of food safety and microbial contamination during production, harvesting, packing and fresh-cut processing of horticultural crops, and were designed to provide methods of contamination avoidance. Coverage includes policy and practices in the United States, Mexico and Central America, Europe, and Japan. Addresses food-borne contaminations from a prevention view, providing proactive solutions to the problems Covers core sources of contamination and methods for identifying those sources Includes best practice and regulatory information

Natural Pathogens of Laboratory Animals

Their Effects on Research

Author: David G. Baker

Publisher: Amer Society for Microbiology

ISBN: N.A

Category: Medical

Page: 385

View: 6374

the only single source of information on natural pathogens of mice, rats, gerbils, hamsters, guinea pigs, rabbits, ferrets, cats, dogs, swine, and non–human primates; quick reference to 158 of the most common infectious agents; information on each pathogen is presented in an easy–to–use format; provides the reader with current information on all aspects of infectious disease.

Myosins

A Superfamily of Molecular Motors

Author: Lynne M. Coluccio

Publisher: Springer Science & Business Media

ISBN: 1402065191

Category: Science

Page: 477

View: 1890

This highly authoritative volume highlights the remarkable superfamily of molecular motors called myosins, which are involved in such diverse cellular functions as muscle contraction, intracellular transport, cell migration and cell division. In a timely compilation of chapters written by leading research groups that have made key discoveries in the field, the current understanding of the molecular mechanisms and biological functions of these intriguing proteins is explored.

MACPF/CDC Proteins - Agents of Defence, Attack and Invasion

Author: Gregor Anderluh,Robert Gilbert

Publisher: Springer

ISBN: 9401788812

Category: Medical

Page: 329

View: 1647

This book focusses on evolutionary, structural and functional aspects of pore-forming proteins, bringing together prominent researchers in the fields of structural biology and cellular and biophysical techniques. The focus is on the MACPF/CDC protein super family that was originally discovered because of unexpected structural similarity between a domain present in bacterial cholesterol-dependent cytolysins (CDC) and proteins of the membrane attack complex/perforin (MACPF) family. Members of the MACPF/CDC super family are crucial for many biological processes, being efficient agents of development, defence, attack and invasion of cells and tissues. However, their best-known role is in bacterial pathogenesis and the proper functioning of the vertebrate immune system, via formation of transmembrane pores in target cell membranes. The book contains chapters on the distribution of MACPF/CDC proteins and on aspects of their evolution and structural properties, the similarities between different super family members and functional properties of some of the best known examples. The book also contains an overview of biophysical approaches that may be used in the future to provide further insights into how these interesting proteins function.

Essentials of Veterinary Parasitology

Author: Hany Elsheikha,Naveed Ahmed Khan

Publisher: Horizon Scientific Press

ISBN: 1904455794

Category: Medical

Page: 221

View: 2422

Essentials of Veterinary Parasitology provides an up-to-date resource for students and practicing veterinarians on how to recognize, diagnose, and treat parasitic diseases in livestock and companion animals. Featuring full-color illustrations and a user-friendly layout, the book begins with a section dedicated to the fundamentals of veterinary parasitology and ends with a section on the prevention of parasitic infections, entailing recent developments in the understanding of the pathogenesis and control of parasitic diseases. In between, there are sections on important parasitic infections in livestock, organized by the parasite agents - helminths, protozoa, and arthropods - plus a section on diagnostic parasitology. This book is an essential reference for veterinary students, practicing veterinarians, and researchers in the field of parasitology.

Cellular Peptidases in Immune Functions and Diseases 2

Author: Jürgen Langner,Siegfried Ansorge

Publisher: Springer Science & Business Media

ISBN: 0306468263

Category: Medical

Page: 522

View: 7655

Treatment and Prevention of Malaria

Antimalarial Drug Chemistry, Action and Use

Author: Henry M. Staines,Sanjeev Krishna

Publisher: Springer Science & Business Media

ISBN: 3034604793

Category: Medical

Page: 318

View: 2582

Malaria has defeated previous efforts at eradication and remains a massive global public health problem despite being readily preventable and treatable. It is a devastating disease that also extracts huge economic costs from the poorest countries in endemic regions. Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs. There is particular emphasis on artemisinins and related peroxides, as these drugs have now become the frontline treatment for malaria. Next generation antimalarials, molecular markers for detecting resistance, the importance of diagnostics and disease prevention are also covered in detail.

Giardia

A Model Organism

Author: Hugo D. Lujan,Staffan Svärd

Publisher: Springer Science & Business Media

ISBN: 3709101980

Category: Medical

Page: 420

View: 6026

Giardia is a relatively simple eukaryotic microbe, causing acute and chronic diarrhea which has been used as a model to understand complex biological processes occurring in eukaryotic cells. Further, due to its parasitic lifestyle, Giardia is an excellent system for the study of the mechanisms of adaptation and cell differentiation from the perspectives of molecular and cell biology. This book presents a comprehensive review of the current state of knowledge regarding all aspects of Giardia’s biology, including epidemiology, cell and molecular biology, genetics, pathogenesis, diagnostics, and clinical treatment. It was written by internationally renowned authors, the leading researchers in the field including several chapters with techniques and resources available for the study of this microorganism. Questions that need to be addressed to fully understand the molecular mechanisms of the parasite as well as the cause of its pathology are presented. Furthermore, Giardia’s biology is compared with that of other parasites in relation to their complexity. This volume is an indispensable resource for researchers working with this parasite. It is a “must” for libraries and the bookshelves of everyone interested in the biology of parasites and early-branching eukaryotes.

Waterborne Zoonoses

Author: J. A. Cotruvo,A. Dufour,G. Rees,Jamie Bartram,R. Carr,D. O. Cliver,G. F. Craun,Ronald Fayer,V. P. J. Gannon

Publisher: IWA Publishing

ISBN: 9781843390589

Category: Science

Page: 528

View: 9353

Zoonoses are caused by microorganisms of animal origin that can also infect humans. Apart from human-to-human transmitted pathogens, they are the microorganisms of greatest concern in regard to threats to drinking-water and ambient water safety, now and in the future. A significant number of emerging and re-emerging waterborne zoonotic pathogens have been recognized over recent decades. SARS, E. coli O157:H7, and Cryptosporidium provide examples of zoonoses with waterborne routes of transmission. Developed from an expert workshop of 29 scientists convened by the World Health Organization and the United States Environmental Protection Agency (USEPA), Waterborne Zoonoses: Identification, Causes and Control provides a critical assessment of current knowledge about waterborne zoonoses and identifies strategies and research needs for controlling future emerging waterborne zoonoses. This book provides guidance to agriculturists, veterinarians, worldwide health agencies and water providers to anticipate potential future waterborne disease problems and to determine whether current practices will be protective or whether new approaches need to be deployed to better protect the health of both humans and animals. Contents Expert Consensus An Introduction To Emerging Waterborne Zoonoses and General Control Principles Water-Related Zoonosis Disease Impacts?Geographical Prevalence Epidemiological Data, Case-Studies, and Outbreaks Categories of Waterborne Disease Organisms Analysis of Zoonotic Microorganisms Prevention and Control of Waterborne Zoonoses Risk Assessment and Regulation Future Emerging Waterborne Zoonoses

Find eBook