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Cancer Chemotherapy

Basic Science to the Clinic

Author: Rachel Airley

Publisher: John Wiley & Sons

ISBN:

Category: Medical

Page: 342

View: 300

This textbook is a clear and accessible introduction to the scientific and clinical aspects of the creation, development and administration of drugs or drug regimens used in the treatment of cancer. Unique in its approach, this book enables the student to gain an understanding of the pathological, physiological and molecular processes governing malignancy, whilst also introducing the role of health professionals and scientists in the research and treatment of cancer. The book consolidates all the essential information necessary for a full understanding of cancer chemotherapy, providing an informative, inexpensive and up-to-date coverage of the subject aimed at an undergraduate level readership. Key Features: Incorporates numerous diagrams, tables and illustrations to aid understanding. Examines key pharmacological and pharmaceutical issues such as dosing, toxicity and preparation of anti-cancer drugs. Includes a key chapter of practice essay questions to ease revision. Comprehensive coverage of drugs currently in pre-clinical and clinical development. An indispensable text for undergraduate students studying pharmacy and medicine as well as those doing courses such as molecular biology, biomedical sciences and pharmacology which cover aspects of oncology.

Drug Delivery in Oncology

From Basic Research to Cancer Therapy

Author: Felix Kratz

Publisher: John Wiley & Sons

ISBN:

Category: Medical

Page: 1822

View: 553

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Drug Delivery in Oncology

From Basic Research to Cancer Therapy

Author: Felix Kratz

Publisher: John Wiley & Sons

ISBN:

Category: Medical

Page: 1689

View: 729

In this first authoritative overview on modern cancer chemotherapy 121 international specialists have contributed their experience and recent data for what is likely to become the gold standard in the field. The authors summarize knowledge gained over the past decade, from basic concepts to successful applications in the clinic, covering active and passive targeting strategies as well as tissue-specific approaches. All current and future targeted delivery systems are discussed, from ligand-based to antibody-based polymer-based systems, right up to micro- and nanoparticulate systems. A special section covers the delivery of nucleic acid therapeutics, such as siRNA, miRNA and antisense nucleotides. In each case, a description of the basic technique is followed by a discussion of the latest preclinical and clinical developments in the field. By virtue of its clear and didactic structure, rich illustrative material and summary chapters, this handbook and ready reference enables the efficient transfer of knowledge between different disciplines, from basic research to the clinician and vice versa. It is equally well suited for professionals, researchers and students in medical oncology and cancer biology, and is also excellent for teaching medical students the foundations of 21st century cancer chemotherapy.

Critical Thinking: An Introduction to the Basic Skills - Seventh Edition

Author: William Hughes

Publisher: Broadview Press

ISBN:

Category: Philosophy

Page: 460

View: 420

Critical Thinking is a comprehensive and accessible introduction to the essential skills of good reasoning. The authors provide a thorough treatment of such central topics as deductive and inductive reasoning, logical fallacies, how to recognize and avoid ambiguity, and how to distinguish what is relevant from what is not. Later chapters discuss the application of critical thinking skills to particular topics and tasks, including scientific reasoning, moral reasoning, media analysis, and essay writing. This seventh edition is revised and updated throughout, and includes a new chapter on legal reasoning as well as access to a companion website of additional questions and other useful resources.

The Cancer Solution

Taking Charge of Your Life with Cancer

Author: Jack C. Westman, M.D., M.S.

Publisher: Archway Publishing

ISBN:

Category: Health & Fitness

Page: 310

View: 539

This book should be read as a requirement for anyone diagnosed with cancer. It will serve as a tremendous practical guide for cancer patients and their families. —Thomas N. Seyfried, Professor of biology at Boston College and author of Cancer as a Metabolic Disease: On the Origin, Management, and Prevention of Cancer. This book is a “must read” for every adult as cancer remains our greatest enemy. If you have experience with cancer, via a family member or friend, once you start reading this book, it will be hard to put down. —Peter L. Pedersen, Professor of Biological Chemistry & Oncology, Johns Hopkins University. Dr. Westman’s personal experience with cancer led him to extensively research the state of cancer care. Strengthening the body’s own immune system to prevent and control cancer has shown very promising results, but it is largely ignored by mainstream cancer research and treatment. If you care about winning the war on cancer, this book will motivate you to advocate for more funding for this line of research. —Stephen L. Swanson, Past Chair of the Board of Directors of the American Cancer Society Dr. Westman’s book is amazing, creative, innovative, different, stimulating and outstanding. —Bharat B. Aggarwal, Professor of Cancer Research, University of Texas M. D. Anderson Cancer Center.

Cancer and Aging

From Bench to Clinics

Author: Martine Extermann

Publisher: Karger Medical and Scientific Publishers

ISBN:

Category: Medical

Page: 170

View: 924

Outlining the complex interaction between the two phenomena Cancer is clearly an age-related disease. Recent research in both aging and cancer has demonstrated the complex interaction between the two phenomena. This affects a wide spectrum of research and practice, anywhere from basic research to health care organization. Core examples of these close associations are addressed in this book. Starting with basic research, the first chapters cover cancer development, mTOR inhibition, senescent cells altering the tumor microenvironment, and immune senescence affecting cancer vaccine response. Taking into account the multidisciplinarity of geriatric oncology, several chapters focus on geriatric and oncologic aspects in patient assessment, treatment options, nursing and exercise programs. The book is rounded off by a discussion on the impact of the metabolic syndrome illustrating the interactions between comorbidity and cancer and a chapter on frailty. This book provides the reader with insights that will hopefully foster his or her reflection in their own research and practice to further the development of this most exciting field. Given the aging of the population worldwide and the high prevalence of cancer, it is essential reading not only for oncologists and geriatricians but for all health practitioners.

Treatment of Peritoneal Surface Malignancies, An Issue of Surgical Oncology Clinics, E-Book

Author: Jesus Esquivel

Publisher: Elsevier Health Sciences

ISBN:

Category: Medical

Page: 219

View: 898

This issue of the Surgical Oncology Clinics of North America, Guest Edited by Dr. Jesus Esquivel, will focus on the current status and future directions of the treatment of the most common peritoneal surface malignancies: appendix cancer, colorectal cancer, ovarian cancer, gastric cancer, and peritoneal mesothelioma. This issue will also outline some of the most common issues that arise regarding cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC), such as pharmacokinetic rationale of heat and intraperitoneal chemotherapy, HIPEC techniques and safety considerations, how to start a peritoneal surface malignancy program, anesthesia considerations during cytoreductive surgery and HIPEC, patient selection for cytoreductive surgery and HIPEC, and the role of dystemic chemotherapy in the management of peritoneal surface malignancies of appendiceal and colorectal origin.

Nutrition and the Cancer Patient

Author: Egidio Del Fabbro

Publisher: Oxford University Press, USA

ISBN:

Category: Medical

Page: 519

View: 138

Nutrition, appetite, and involuntary weight loss are issues that affect a large number of cancer patients and cancer survivors. Aspects such as symptom management, behavioural modification, exercise and medication are all important aspects of cancer care, but nutritional issues at the end of life can be accompanied by contentious ethical factors as well as religious and cultural influences that need to be addressed by health professionals. This book enables physicians, nurses and also dieticians to better discuss these complex issues with patients and their families. This comprehensive reference book provides both background information and practical, clinical advice for managing the cancer patient at all stages of their disease trajectory. It includes information that relates to patients who are continuing to receive disease-specific therapy, the cancer survivor, as well as patients with advanced or recurrent cancer receiving palliative care. Basic principles such as epidemiology and physiology set the scene, leading into the cachexia/anorexia syndrome, treatment options, nutritional counselling, enteral and parenteral nutrition, complementary/alternative therapies, exercise, clinical outcomes measures in each of the clinical groups, and focus on special populations and their specific needs. Multidimensional, interdisciplinary clinical evaluation and treatment is emphasised, and ethical, religious, and cultural factors are also addressed. Multidisciplinary in nature, this book draws on the experience of the editors' work across the fields of oncology, palliative care, surgery, primary care, nursing, dietetics and nutritional science. It will prove invaluable to all general practitioners, internists, medical oncologists and surgeons, nurses, palliative care specialists and related professionals involved in the care of the cancer patient.

Current Cancer Research 2002

Author: Deutsches Krebsforschungszentrum

Publisher: Springer Science & Business Media

ISBN:

Category: Medical

Page: 348

View: 868

Adult and Embryonic Stem Cells

Author: Kursad Turksen

Publisher: Springer Science & Business Media

ISBN:

Category: Science

Page: 262

View: 895

This volume will cover a series of reviews on stem cells including adult and embryonic stem cells. Speakers were invited to present these talks during the Stem Cell Symposia in fall of 2010, in Samsun, Turkey. Unique aspect of this volume is that it brings a multidisciplinary aspect of stem cells extracted from a symposium.

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